
Dr. Sospeter Njeru
Ag Deputy Director CCDR
Dr. Njeru has an academic background in biochemistry and biomedical sciences. My research competence cut across the fields of drug discovery, cancer biology, immunology, biological aging and how our environment influence our vulnerability or resilience to diseases. In my training and research activities at Leibniz Institute on Ageing, Paul Ehrlich Institute – Germany, and Kenya Medical Research Institute (KEMRI), he has acquired valuable sets of multi-Omic and biochemistry skills including, developing an easy to use library preparation method for NGS RNA-sequencing, preparing samples for proteomics, Lipidomics, Peptidomics, and Nanostring.
In addition, Dr. Njeru has is proficient in Western blotting, PCR approaches, Immunohistochemistry and Immunocytochemistry, cell culture, CRISPR/Cas9 knockout, CRISPRi, and shRNA knockdown approaches, among others. He has used these approaches to decipher molecular targets and mechanistic changes upon genetic manipulation or chemical treatments in both in vitro and in vivo experimental model systems.
Presently, he is part of a team that is using community participatory approaches to profile disease burdens, vulnerability and/or resilience as people transition from rural to urban lifestyle in the context of Turkana Health Genomic Project (THGP). He is also part of an African consortia – Grand Challenges Africa Drug Discovery Accelerator (GC-ADDA), where we are promoting drug discovery initiatives in Africa-specifically contributing on the use of BacPROTAC as potential innovative therapeutic approach against Mycobacteria tuberculosis. As a way of giving back to the community and building the next crop of African scientists, Dr. Njeru mentors young scientists in Africa through initiatives such as KEMRI Graduate School (KGS), Pan African University Institute for Basic Sciences, Technology and Innovation (PAUSTI), German academic exchange service (DAAD), Turkana Health genomic Project (THGP) and Afrique Research Support Hub (ARSH) Program
Education
| INSTITUTION AND LOCATION | DEGREE | COMPLETION DATE | FIELD OF STUDY |
| Paul Ehrlich Institute, Langen (Hessen)-Germany | Post-Doc | 03/2021 | Immunology |
|
Friedrich-Schiller Universität, Jena-Germany |
Doctorate |
05/2019 |
Biochemistry |
|
Egerton University, Nakuru-Kenya |
M.Sc. |
12/2010 |
Biochemistry |
|
Egerton University, Nakuru-Kenya |
B.Sc. |
07/2008 |
Biomedical Science & Technology |
Positions and Scientific Appointments
- 2024/09-to date Centre Head/Deputy Director, Centre for Community Driven Research (CCDR)-KEMRI Kirinyaga
- 2023/09-to date Principal Research Scientist, KEMRI-Kenya
- 2021/04-2023/08 Assistant Principal Research Scientist, KEMRI-Kenya
- 2021/04-to date Lecturer of Biochemistry and Immunology, KEMRI Graduate School
- 2019/09 -2021/03 Post-Doctoral scientist, Paul Ehrlich Institute-Germany
- 2014/03 – 2019/08 Doctoral candidate/guest scientist, Leibniz Institute on Ageing (FLI)-Germany
- 2012/07 – 2021/12 University Lecturer, Kisii University
- 2009/08 – 2012/06 Adjunct University Lecturer, Mount Kenya University and Egerton University
Positions and Scientific Appointments
- Title: Environmental and genetic effects on health of Turkana Community of Kenya
Funding agency: National Institute of Health (NIH) and UC Berkeley.
Period: 2023-2027
Sum: USD 119,917
Role: Site-Principal Investigator
- Title: Research and development of a novel natural product based non-hormonal female contraceptive
Funding agency: Gates Foundation through Grand Challenges Africa and Science for Africa Foundation
Period: 2024-2026
Sum: USD 350,000
Role: co-Investigator
- Title: Pursuing Targeted Protein Degradation as a New Strategy for Antituberculosis Drug Development under Grand Challenges African Drug Discovery Accelerator-Tuberculosis (GC ADDA-TB) program.
Funding agency: LifeArc and the Gates Foundation
Period: 2024-2026
Sum: Sub-award of USD 311,000
Role: co-Investigator
- Title: Identification of novel antibacterial endophyte-derived lead compounds targeting ESKAPE pathogens
Funding agency; TWAS
Period; 2022-2023
Sum: USD 29,000
Role: co-Principal Investigator
- Title: Efficacy of selected Indigenous Medicinal Plants from Mbeere and Tharaka Communities of Kenya Against ESKAPE-E and Enteric Parasites
Funding agency; Internal Research Grant (IRG)-KEMRI
Period; 2024-2028
Sum: USD 200,000
Role: co-Principal Investigator/Co-Applicant
- Title: Efficacy of plant-derived compounds from selected Kenyan indigenous medicinal plants and their potential mode of action against multidrug-resistant ESKAPE pathogens
Funding agency; IRG-KEMRI
Period; 2024-2028
Sum: USD 50,000
Role: co-Principal Investigator/Co-Applicant
- Title: Discovery of anticancer lead compound(s) from selected medicinal plants from Mbeere sub-counties, Embu County and determination of their molecular target(s) & mechanism(s) of action.
Funding agency; IRG-KEMRI
Period; 2023-2025
Sum: USD 30,000
Role: Principal Investigator/Main Applicant
- Title: Analysis of a Potential Boost of Anti-Leishmanial T Cell Responses after in vitro Modulation with Nivolumab (PD-1 Checkpoint Inhibitor) in Patients with Visceral Leishmaniasis
Funding agency; DRUID FLEX Fund in collaboration with Paul-Ehrlich Institute
Period; 2021-2023
Sum: USD 23,000
Role: Principal Investigator/Main Applicant
Publications
- Robi Chacha, Caroline Maina, Edwin Murungi, Eric Guantai, Mathew P Ngugi, Ephantus Ndirangu, James Mugo, Sospeter Ngoci Njeru, Elizabeth Kigondu. Potentiation of the antimycobacterial activity of bedaquiline, clofazimine, and doxycycline against Mycobacterium smegmatis by several natural product-based compounds is putatively via efflux inhibition [version 1; peer review: 2 approved with reservations]. Open Res Africa 2025, 8:23 (https://doi.org/10.12688/openresafrica.16071.1)
- Ephantus G Ndirangu, Caroline N Maina, Edwin K Murungi, Margaret M Ng’ang’a, Robi Chacha, Moses N Kehongo, Sospeter N Njeru, Nuhu I Tukur, Gabriel T Mashabela, Digby F Warneh, Paul R Race, Elizabeth M Kigondu. Identification of mycobacterial efflux pump inhibiting compounds from Berberis holstii Engl. and determination of their mechanism of action. [Preprint -bioRxiv]; https://doi.org/10.1101/2025.08.15.670474.
- Marina M Watowich, Layla Brassington, Amy Longtin, Selina Wang, Ryan Rossow, Kathleen D Reinhardt, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles Miano, Benjamin Muhoya, Boniface Mukoma, Tan Bee Ting A/P Tan Boon Huat, Kar Lye Tam, Yvonne AL Lim, Dino Martins, Sospeter Ngoci Njeru, Kee Seong Ng, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Michael Gurven, Thomas S Kraft, Amanda J Lea. Urbanization exacerbates age-associated declines in cardiometabolic health in Turkana and Orang Asli. [Preprint – medRxiv]. https://pubmed.ncbi.nlm.nih.gov/?term=njeru+sn&sort=date.
- Inyani JL Lagu, Rakita Letoluo, Sally W Kamau, James M Kuria, Fredrick M Musila, Vyacheslav Kungurtsev, Dorothy W Nyamai, Sospeter N Njeru. Antiproliferative Activity, Phytochemistry, Network Pharmacology, Molecular Docking and Gene Expression Analysis of Maerua edulis Extracts against Human Cervical Cancer Cell Line. Submitted to BMC Complementary and Alternative Medicine. (under Revision: Minor Review) doi: https://doi.org/10.1101/2025.01.07.631450.
- Marina Watowich, Audrey M Arner, Selina Wang, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles M Mwai, Benjamin Muhoya, Boniface Mukoma, Kar Lye Tam Tam, Tan Bee Ting A/P Tan Boon Huat, Michael Gurven, Yvonne AL Lim, Dino Martins, Sospeter Njeru, Ng Kee Seong, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Thomas S Kraft, Amanda J Lea. The built environment is more predictive of cardiometabolic health than other aspects of lifestyle in two rapidly transitioning Indigenous populations. [Preprint – medRxiv]. doi: 10.1101/2024.08.26.24312234. (https://pubmed.ncbi.nlm.nih.gov/39252903/).
- Audrey M Arner, Benjamin Muhoya, Mitchell Sanchez Rozado, Michael R Gurven, John Kahumbu, Joseph Kamau, Patriciah Kinyua, Francis Lotukoi, Dino J Martins, Charles Miano, Michael J Montague, Sospeter Njeru, Julie Peng, Peter Straub, Marina M Watowich, Lea K Davis, Noah Snyder-Mackler, Julien F Ayroles, Amanda J Lea. Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch. [Pre-print – bioRxiv]; https://doi.org/10.1101/2024.02.13.580011).
- Sally Wambui Kamau, Mercy Jepkorir, Gilbert Kipkoech, Inyani John Lino Lagu, Wesley Kanda, Susan Kibunja, Rakita Letoluo, Shadrack Barmasai, Alice Wanyoko, Vincent Ruttoh, James Kuria, Peter Githaiga Mwitari, Mathew Piero Ngugi, Sospeter Ngoci Njeru. Antiproliferative Activity of Grewia villosa Ethyl Acetate Extract on Cervical Cancer HeLa Cell lines: Mechanistic Insights through Network Pharmacology and Functional Assays Approach. Plos One (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0331649).
- AJ Lea, IV Caldas, KM Garske, ER Gerlinger, JP Arroyo, J Echwa, M Gurven, C Handley, J Kahumbu, J Kamau, P Kinyua, F Lotukoi, A Lopurudoi, S Lowasa, SN Njeru, R Mallarino, D Martins, PW Messer, C Miano, B Muhoya, J Peng, T Phung, JD Rabinowitz, A Roichman, R Siford, AC Stone, AM Taravella Oill S Mathew, MA Wilson, JF Ayroles (2025). Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. Science (https://www.science.org/doi/10.1126/science.adv2467).
- Kamau SW, Ngugi MP, Mwitari PG, Njeru SN (2024). Network pharmacology, molecular docking and experimental approaches of the anti-proliferative effects of Rhamnus prinoides ethyl-acetate extract in cervical cancer cells. Heliyon. 2024 Sep 2;10(17):e37324. doi: 10.1016/j.heliyon.2024.e37324. eCollection 2024 Sep 15. (https://pubmed.ncbi.nlm.nih.gov/39290290/)
- Peter C. de Greef†, Sospeter Ngoci Njeru†, Claudia Benz†|, Simon Fillatreau, Bernard Malissen, Fabien Agenès,Rob J. de Boer, and Jörg Kirberg (2024). The TCR assigns naive T cells to a preferred lymph node. Science Advances; (https://www.science.org/doi/full/10.1126/sciadv.adl0796).
- Okpako IO, Atieno Ng’ong’a F, Kyama CM, Njeru SN. Network pharmacology, molecular docking, and in vitro study on Aspilia pluriseta against prostate cancer, BMC Complementary and Alternative Medicine. https://pubmed.ncbi.nlm.nih.gov/39304868/
- Inyani John Lino Lagu, Dorothy Wavinya Nyamai and Sospeter Ngoci Njeru. (2024): Phytochemical Analysis, In-Vitro and In-Silico Study of Antiproliferative Activity of Ethyl Acetate Fraction of Launaea cornuta against Human Cervical Cancer Cell Line, Frontiers in Pharmacology-Ethnopharmacology, https://doi.org/10.3389/fphar.2024.1399885.
- Chiamah OC, Atieno D, Karani L, Chepng’etich J, Osano M, Gachie B, Kipkoech G, Jepkorir M, Ndungu JW, Kuria J, Kimani F, Njeru SN, Gathirwa JW . Evaluation of the antimalarial properties of Solanum incanum L. leaf extract fractions and its ability to downregulate delta aminolevulinate dehydratase to prevent the establishment of malaria infection. Journal of Ethnopharmacology, doi: 10.1016/j.jep.2023.117613, 2024 Jan 5:117613. (https://pubmed.ncbi.nlm.nih.gov/38185259/).
- Irungu B, Okari E, Nyangi M, Njeru S, Koech L. Potential of medicinal plants as antimalarial agents: a review of work done at Kenya Medical Research Institute. Front Pharmacol. 2023 Oct 20;14:1268924. doi: 10.3389/fphar.2023.1268924. eCollection 2023.( https://pubmed.ncbi.nlm.nih.gov/37927601/).
- Maiyo Z, Njeru SN, Toroitich FJ, Indieka SA, Obonyo MA. Ethnobotanical Study of Medicinal Plants Used by the People of Mosop, Nandi County in Kenya. Frontiers in Pharmacology.;14:1328903. (https://www.frontiersin.org/articles/10.3389/fphar.2023.1328903/full).
- Okpako IO, Atieno Ng’ong’a F, Kyama CM, Njeru SN. Antiproliferative activity of ethyl acetate fraction of Euphorbia ingens against prostate cancer cell line: An in silico and in vitro analysis. Scientific African. 2023 Nov 1;22:e01943. (https://www.sciencedirect.com/science/article/pii/S2468227623003988).
- Innocent Oluwaseun Okpako, Florence A. Ng’ong’a, Mutinda C. Kyama and Sospeter N. Njeru. Phytochemical screening and gas chromatography-mass spectrometry analysis of Euphorbia ingens organic root extract, Journal of Medicinal Plants Research, https://doi.org/10.5897/JMPR2022.7287 (https://academicjournals.org/journal/JMPR/article-abstract/F6A5E1D70510).
- Muema JM, Bargul JL, Obonyo MA, Njeru SN, Matoke-Muhia D, Mutunga JM. Contemporary exploitation of natural products for arthropod-borne pathogen transmission-blocking interventions (Review), Parasit Vectors. 2022 Aug 24;15(1):298. doi: 10.1186/s13071-022-05367-8. (https://pubmed.ncbi.nlm.nih.gov/36002857/).
- Muema, J.M., Bargul, J.L., Mutunga, J.M., Obonyo, M.A., Asudi, G.O. and Njeru, S.N. Neurotoxic Zanthoxylum chalybeum root constituents invoke mosquito larval growth retardation through ecdysteroidogenic CYP450s transcriptional perturbations. Pesticide Biochemistry and Physiology, 2021: p. 104912. (https://www.sciencedirect.com/science/article/abs/pii/S0048357521001437)
- Njeru SN*, Muema JM. In Vitro Cytotoxicity of Aspilia Pluriseta Schweinf. Extract Fractions, BMC Research Notes. 2021 Feb 9;14(1):57. doi: 10.1186/s13104-021-05472-4.( https://pubmed.ncbi.nlm.nih.gov/33563333/)
- Njeru SN*, Muema JM. Antimicrobial activity, phytochemical characterization and gas chromatography-mass spectrometry analysis of Aspilia pluriseta Schweinf. extracts. Cell Press – Heliyon. 2020 Oct 8;6(10):e05195. doi: 10.1016/j.heliyon.2020.e05195. PMID: 33083626; PMCID: PMC7551365. (https://pubmed.ncbi.nlm.nih.gov/33083626).
- Njeru SN, Kraus J, Meena JK, Lechel A, Katz SF, Kumar M, Knippschild U, Azoitei A, Wezel F, Bolenz C, Leithäuser F, Gollowitzer A, Omrani O, Hoischen C, Koeberle A, Kestler HA, Günes C, Rudolph KL. Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. Oncogene. 2020 Feb;39(7):1445-1465. doi: 10.1038/s41388-019-1073-2. Epub 2019 Oct 28. PMID: 31659255.. https://www.nature.com/articles/s41388-019-1073-2.
- Chen Z, Amro EM, Becker F, Hölzer M, Rasa SMM, Njeru SN, Han B, Di Sanzo S, Chen Y, Tang D, Tao S, Haenold R, Groth M, Romanov VS, Kirkpatrick JM, Kraus JM, Kestler HA, Marz M, Ori A, Neri F, Morita Y, Rudolph KL. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019 Jan 7;216(1):152-175. doi: 10.1084/jem.20181505. Epub 2018 Dec 7. PMID: 30530755; PMCID: PMC6314529, (https://pubmed.ncbi.nlm.nih.gov/30530755/).
- Muema JM, Nyanjom SG, Mutunga JM, Njeru SN, Bargul JL. Green tea proanthocyanidins cause impairment of hormone-regulated larval development and reproductive fitness via repression of juvenile hormone acid methyltransferase, insulin-like peptide and cytochrome P450 genes in Anopheles gambiae sensu stricto. PLoS One. 2017 Mar 16;12(3):e0173564. doi: 10.1371/journal.pone.0173564. PMID: 28301607; PMCID: PMC5354366, (https://pubmed.ncbi.nlm.nih.gov/28301607).
- Muema JM, Bargul JL, Njeru SN, Onyango JO, Imbahale SS (2017). Prospects for malaria control through manipulation of mosquito larval habitats and olfactory-mediated behavioural responses using plant-derived compounds. Parasites & Vectors, 2017 Apr 17;10(1):184. doi: 10.1186/s13071-017-2122-8. Review. https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2122-8
- Muema JM, Njeru SN, Colombier C, Marubu RM. Methanolic extract of Agerantum conyzoides exhibited toxicity and growth disruption activities against Anopheles gambiae sensu stricto and Anopheles arabiensis larvae. BMC Complement Altern Med. 2016 Nov 22;16(1):475. doi: 10.1186/s12906-016-1464-7. PMID: 27876055; PMCID: PMC5120420. https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-016-1464-7.
- Muema JM, Bargul JL, Nyanjom SG, Mutunga JM, Njeru SN (2016). Potential of Camellia sinensis proanthocyanidins-rich fraction for controlling malaria mosquito populations through disruption of larval development. Parasites & Vectors 2016, 9:512, DOI:10.1186/s13071-016-1789-6. http://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1789-6.
- Njeru SN*, Obonyo M, Nyambati S, Ngari S, Mwakubambanya R, Mavura H. (2016). Antimicrobial and cytotoxicity properties of the organic solvent fractions of Clerodendrum myricoides (Hochst.) R. Br. ex Vatke: Kenyan traditional medicinal plant. Journal of Intercultural Ethnopharmacology. 2016 Apr 16;5(3):226-32. doi: 10.5455/jice.20160416122003. www.ncbi.nlm.nih.gov/pubmed/27366347.
- Sospeter Ngoci Njeru* and Meshack Amos Obonyo (2016). Potency of extracts of selected plant species from Mbeere, Embu County-Kenya against Mycobacterium tuberculosis. Journal of Medicinal Plants Research, Vol. 10(12), pp. 149-157. www.academicjournals.org/journal/JMPR/article-full-text-pdf/56A41D257906.
- Sospeter Ngoci Njeru*, Meshack Amos Obonyo, Samwel Onsarigo Nyambati, Silas Mwaniki Ngari (2015). Antimicrobial and cytotoxicity properties of the crude extracts and fractions of Premna resinosa (Hochst.) Schauer (Compositae): Kenyan traditional medicinal plant. BMC Complementary and Alternative Medicine. http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0811-4
- Sospeter Ngoci Njeru*, Meshack A. Obonyo, Samwel O. Nyambati, Silas M. Ngari (2015). Bioactivity of Cissampelos pareira medicinal plant against Mycobacterium tuberculosis. Journal of Pharmacognosy and Phytochemistry www.phytojournal.com/vol3Issue6/4-1-1.1.html.
- Sospeter Ngoci, Njeru*, Samwel Onsarigo, Nyambati, Meshack Amos, Obonyo, Silas Mwaniki, Ngari, Paul Kuria, Kamweru, John Mwaniki, Njeru (2015). Piliostigma thonningii Extract Fractions have Antituberculous, Antibacterial and Antifungal Activity within the acceptable Toxicity Limits. Journal of Medicinal Plants Research www.academicjournals.org/journal/JMPR/article-abstract/4A8D49653732.
- Sospeter Njeru Ngoci*, Josphat C. Matasyoh, Charles Gathinji Mwaniki, and Charles Maina Mwendia. (2012). Antibacterial activity of methanol root extract of Indigofera lupatana Baker F. Eastern Journal of Medicine, 17(1): 11-16 www.easternjmed.org/PDF/2012_1/11.pdf; ISSN 1339-3886
- Ngoci, S. N*., Mwendia, C. M., and Mwaniki, C. G. (2011). Phytochemical and cytotoxicity testing of Indigofera lupatana Baker F. Journal of Animal & Plant Sciences, 11(1): 1364-1373 < http://www.biosciences.elewa.org/JAPS; ISSN 2071 – 7024>
Complete List of Published Work in My Bibliography:

Florence M Kinyua
Research Scientist
Ms. Florence Public Health Scientist with 10+ years’ experience in implementation science, social and behavioral research, and community-based interventions in resource-limited settings. Expertise in participatory approaches, digital health, and health systems strengthening, with leadership in studies on treatment adherence, HPV vaccination, nutrition, and community health programs across Kenya.
Her scientific contributions span digital health, community-based prevention, health systems strengthening, and social and behavioral research in resource-limited settings. Early work demonstrated the feasibility of mobile phone–based reminders to support antiretroviral therapy adherence among people living with HIV in Kenya, informing later national digital adherence initiatives. I have co-led participatory community interventions, including an HPV vaccine pilot using mobile follow-up reminders and a nutrition-based schistosomiasis prevention project, showing that community-embedded approaches improve uptake and sustainability. As Regional Manager at ERMIS Africa, she oversaw environmental and public health projects across seven Kenyan counties, generating evidence on how sanitation, clean energy, and governance interventions improve health and livelihoods.
Across my career, she has applied mixed-methods and participatory research to understand health behaviors, barriers to care, and disease prevention strategies, integrating behavioral insights into intervention design. These experiences underpin my capacity to guide community training, mobile health interventions, and co-designed solutions for prevalent health challenges.
Education
- PhD (Public Health, ongoing) – Jomo Kenyatta University of Agriculture & Technology (2022–Date)
- MSc (Public Health) – Jomo Kenyatta University of Agriculture & Technology (2016)
- BSc (Biochemistry, First Class Honors) – University of Nairobi (2010)
- Certificates/Short courses: Proposal writing, Concept development, Research methodology, Mentorship, Clinical Trial Monitoring, Fundamentals of Bioethics, Data analysis (SPSS, STATA, R, GIS), AI for Scientists (Microsoft), Leadership & Management (RedR/Oxfam), Children’s Psychology
Positions and Scientific Appointments
- Performance Contract Champion (2025-Date) to KEMRI Centre for Community Driven Research
- CSC Secretary (2025-Date): KEMRI CCDR Center Scientific Committee
- Research Scientist (2023-Date): KEMRI Centre for Community Driven Research
- Grants Committee Secretary & member (2022): KEMRI Graduate School: Drafting of proposals for the center and mentoring students on grants writing
- Data Manager (2020–2021): KEMRI VHF Laboratories –COVID-19 national surveillance
- Research Scientist (2019): Kirinyaga; Nutrition “Uji Plus” pilot study
- Lecturer (2017–2019): Meru University of Science & Technology – Community and Public Health
- Regional Manager (2013–2016): ERMIS Africa – Environmental health and sanitation projects in 7 counties
- Program Officer (2011–2013): ERMIS Africa – Community surveys, monitoring & evaluation
Positions and Scientific Appointments
- Study Cordinator & Data Manager for the project on field evaluation of Covid-19 antigen testing kits in selected regions of Kenya 2022-2023.
- Monitoring & Evaluation Officer & Data manager for the project: Acceptability and effectiveness of Ujiplus®- aschool meal fortified with a natural anthelminthic agent for control of Schistosomamansoni, 2019-2020.
- Principal Investigator for the project: Perceptions of HIV infected patients on the use of cell phone as a tool to support their antiretroviral adherence; a cross-sectional study in a large referral hospital in Kenya, 2011-2013
- Data scientist: for the project : Switch from 200 to 350 CD4 baseline count: what it means to HIV care and treatment programs in Kenya.
- Project officer & data scientist for project: Electronic Waste Management in Kenya: Mapping and Implications for Environmental Management. ERMIS Africa, 2012.
Publications
- Matey E, Kinyua F, Kattam A, Chege S, Maina G, Otieno DP, Songok E:
Acceptability and effectiveness of Ujiplus®- aschool meal fortified with a naturalanthelminthic agent for control of Schistosomamansoni, International Journal of Infectious Diseases, Volume 101, 306, 2020; DOI: 1016/j.ijid.2020.09.800 - Florence K, Michael K, Gideon K, Joseph M, Adrienne FA, Peter M and Songok E. Perceptions of HIV infected patients on the use of cell phone as a tool to support their antiretroviral adherence; a cross-sectional study in a large referral hospital in Kenya. BMC Public Health 2013, 13:987 http://www.biomedcentral.com/1471-2458/13/987
- Florence K, Michael K, Gideon K, Joseph M, Adrienne FA, Peter M and Songok E. Perceptions of HIV infected patients on the use of cell phone as a tool to support their antiretroviral adherence; a cross-sectional study in a large referral hospital in Kenya. NACC Book of Abstracts 2013, A031:33
- Mwangi J, Ngángá Z, Lihana R, Lagat N, Kinyua J, Muriuki J, Maiyo A, Kinyua F, Okoth F, Mpoke S. Switch from 200 to 350 CD4 baseline count: what it means to HIV care and treatment programs in Kenya. The Pan African Medical Journal. 2012; 12:80.
- Muchemi J., Karume M., Kinyua F., Muniale F. Electronic Waste Management in Kenya: Mapping and Implications for Environmental Management. ERMIS Africa, 2012. ISBN 978-9966-7321-2-8

Mr. Charles M. Mwai
Research Scientist
Mr. Charles’ work reflects a career defined by breadth, adaptability, and meaningful impact. He was trained as a biochemist at the undergraduate level and is a scholar in the Master of Science in Molecular Medicine program at the KEMRI Graduate School of Health Sciences. His academic training and research interests center on evolutionary medicine and population genomics. Specifically, he investigates how environmental factors associated with lifestyle transitions—such as rural-to-urban migration—interact with pathogen exposure and infections to influence immune function, dysregulation, and adaptive processes.
Through strategic collaborations with co–principal investigators at leading global institutions, including Princeton University, University of California, Vanderbilt University, and University of the Witwatersrand, Mr. Charles has contributed to leading immunological and transcriptomic profiling of peripheral blood mononuclear cells in both field and laboratory settings. This work generated novel genomic insights into renal physiology and metabolic regulation associated with pastoralist populations in Turkana. The findings were published in Science Advances and stand as a testament to equitable and impactful international collaboration. This achievement further positions Kenya—particularly KEMRI, through CCDR—and sub-Saharan Africa at the forefront of scientific discovery.
Building on this foundation, Mr. Charles is motivated to advance the integration of single-cell genomics, cytokine signaling, and network modeling approaches to connect molecular immune regulation with the ecological and evolutionary forces that shape it. This vision represents his primary focus for funding mobilization and serves as a platform for sustained partnerships, scientific learning, and capacity building.
Education
- Research Residency-VSRC (Gene x Environment interactions) | May 2024
Princeton University at EEB, Lewis Sigler institute of integrative genomics, (Prof. Ayroles Lab)
- Graduate Student apprentice in Bioethics | Jan 2024.
KEMRI-CBEC in Karachi, Funded through the International Research Ethics Education and Curriculum Development Award-R25, Fogarty International Centre for the US National Institute of Health (Capacity building)
- Master of Science in Molecular Medicine | May 2023.
KEMRI Graduate school of health sciences (KGS)
- Bachelor of Science in Biochemistry. | Sep 2021.
The University of Embu (UoEM) SPAS
Positions and Scientific Appointments
May 2025 to date. Tutorial Fellow and Lab Instructor, KEMRI Graduate School (KGS)
(Molecular medicine)
Nov 2024 to date. Graduate on research, associate– George Washington University School of
Medicine and Health Sciences, MITM Department (Dr. Gazzinelli lab)
Oct 2021 to date. Research Scientist– Turkana Health and Genomics Project, KEMRI.
Projects associated with member
The Turkana Health and Genomics project– Since 2018 to date
An international and collaborative project studying the role of genotype and lifestyle change on human health. Major objectives being contrasting between transcriptomic and phenotypic data to not only allow us retrace human evolutionary history but also understand how disruption of locally adapted systems may lead to disease. |NIH Funded.
Projects associated with member
2025:
- AJ Lea, IV Caldas, KM Garske, ER Gerlinger, JP Arroyo, J Echwa, M Gurven, C Handley, JC Kahumbu, J Kamau, P Kinyua, F Lotukoi, A Lopurudoi, S Lowasa, SN Njeru, R Mallarino, DJ Martins, PW Messer, C Miano, B Muhoya, J Peng, T Phung, JD Rabinowitz, A Roichman, R Siford, AC Stone, AM Taravella Oill, S Mathew, MA Wilson, JF Ayroles. (2025). Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. Science, 389(6766), 1246-1251. https://doi.org/10.1126/science.adv2467
- Marina M Watowich, Layla Brassington, Amy Longtin, Selina Wang, Ryan Rossow, Kathleen D Reinhardt, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles Miano, Benjamin Muhoya, Boniface Mukoma, Kar Lye Tam, Yvonne AL Lim, Dino Martins, Sospeter Ngoci Njeru, Kee Seong Ng, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Michael Gurven, Thomas S Kraft, Amanda J Lea. (2025). Urbanization exacerbates age-associated declines in cardiometabolic health in Turkana and Orang Asli. doi: https://doi.org/10.1101/2025.06.06.25329160
2024
- Marina M Watowich, Audrey M Arner, Selina Wang, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles M Mwai, Benjamin Muhoya, Boniface Mukoma, Kar Lye Tam, Michael Gurven, Yvonne AL Lim, Dino Martins, Sospeter Njeru, Ng Kee Seong, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Thomas S Kraft, Amanda J Lea. (2024). The built environment is more predictive of cardiometabolic health than other aspects of lifestyle in two rapidly transitioning Indigenous populations. doi: https://doi.org/10.1101/2024.08.26.24312234
- Audrey M Arner, Benjamin Muhoya, Mitchell Sanchez Rozado, Michael Gurven, John Kahumbu, Joseph Kamau, Patriciah Kinyua, Francis Lotukoi, Dino J Martins, Charles Miano, Michael J Montague, Sospeter N Njeru, Julie Peng, Peter Straub, Marina M Watowich, Lea K Davis, Noah Snyder-Mackler, Julien F Ayroles, Amanda J Lea. (2024). Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch. bioRxiv,doi: https://doi.org/10.1101/2024.02.13.580011
Flash talks_ 51st Meeting Human Biology Association | 2026
- Urbanization Does Not Always Mean Loss: Microbiome Diversity Patterns in the Turkana of Kenya. Kahumbu, John; Atkins, Thomas; Henry, Lucas; Kinyua, Patricia; Lea, Amanda; Martins, Dino; Miano, Charles; Muhoya, Benjamin; Ayroles, Julien
Biology of Genomes: Cold Spring Harbor Posters | 2025
- Dysregulation of cellular signaling networks upon rapid environmental shift Thomas K. Atkins, Kristina M. Garske, Charles M. Mwai, Julie Peng, Matt Chao, Emma Gerlinger, John Kahumbu, Boniface Mukoma, Echwa John, Patricia Kinyua, Anjelina Lopurudoi, Nicholas Mutai, Dino Martins, Amanda Lea, Julien F. Ayroles.
Affiliation: Princeton University, Princeton, New Jersey.
https://meetings.cshl.edu/posters/genome25/genome2025_AbstractBook.pdf
- Detection of early metabolic stress mechanisms driving risk for cardiometabolic disorders in an urban- transitioning Kenyan population Kristina M. Garske, Thomas Atkins, Emma Gerlinger, Julie Peng, Matthew Chao, John C. Kahumbu, Varada Abhyankar, Benjamin Muhoya, Charles M. Mwai, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Boniface Mukoma, Dino Martins, Sospeter Njeru, Amanda J. Lea, Julien F. Ayroles.
Affiliation: Princeton University, Princeton, New Jersey.
https://meetings.cshl.edu/posters/genome25/genome2025_AbstractBook.pdf

Ms. Mukami Esther
Research Scientist
Ms. Mukami is a research scientist, working with Kenya Medical Research Institute (KEMRI), at the Center for Community Driven Research (CCDR), Kirinyaga, with a background of Bachelors of Science in Medical Laboratory Science. She has extensive knowledge of laboratory analysis and procedures. She is a certified, licensed and registered with the Kenya Medical Laboratory Technicians and Technologists Board therefore qualifying to draw, handle and analyze human samples both on the field and in the laboratory for clinical and research purposes.
Ms. Mukami is well versed in Microbiology, Biochemistry, Blood banking, Parasitology, Phlebotomy, Serology Histology and Hematology benches. Over the medical trainings in these various benches, She has acquired elaborate laboratory techniques with which she can confidently run and oversee laboratory activities working hand in hand with my team members. For the safety of the team members and public members she is well trained and certified in biosafety and biosecurity techniques, under the National Laboratory Service (NLS) to ensure safe handling and containment of infectious micro-organisms and hazardous biological materials in the laboratory setting and protect the public health during field work.
Under the affiliation of KEMRI, she has been able to enroll in The Collaborative Institutional Training Initiative (CITI), under which we train on various subjects dealing with research. This will definitely define the future of my research, as a research scientist.
Education
University of Eastern Africa, Baraton – 2019-2024
- 4 years training in Bachelors of Medical Laboratory Science.
CITI program training under KEMRI affiliation-Jan 2025
- Three weeks training in biomedical research -Basic course/refresher
National Laboratory Service (MOH) – Jan 2025
- Online Biosafety and Biosecurity Annual Refresher Training
National Laboratory Service (MOH) – Jan 2025
- Basic Life Support and Emergency Care Training
National AIDS and STI Control Program (MOH) – Jan 2024
- 15-day Training on HIV Testing and Counselling Course in HIV Prevention Services.
Nakuru County Referral and Teaching Hospital – Dec 2023-March 2024
- 4 months training on, Microbiology, Haematology, Biochemistry, Serology, Parasitology, Blood Banking, Phlebotomy, and Histology clinical laboratory services.
Kapsabet County Teaching and Referral Hospital – Sept 2023-Oct2023
- 2 months training on, Microbiology, Haematology, Biochemistry, Serology, Parasitology, Blood Banking, Comprehensive Care Unit, and Phlebotomy clinical laboratory services.
Positions and Scientific Appointments
- KEMRI, Kirinyaga – Centre for Community Driven Research [CCDR]-From Nov 2024 to dateResearch Scientist.

Ms. Doreen Mwendwa Gikunda
Laboratory Technologist
Ms. Doreen is a lab technologist with a 5 years’ experience in lab safety and management, proper preparation and handling of different lab chemicals and reagents. Besides that, she worked with brookside dairies Ruiru for 3 months whereby she gained knowledge in value addition to milk. Her knowledge in value addition can be used in community projects that have majored in food products. Additionally in the lab she is well versed in the following areas: – chemical analytical methods, instrument faults, diagnosis and maintenance, biological analysis, parasitology, immunology, lab practice and management. Ms Doreen also works with adults aged between ages of 18-25 years in the community. Throughout her working years she has gained leadership skill both at the office level and community level. she also have interest in research proposals on pesticide’s residuals and their contributions to cancer.
Positions and Scientific Appointments
November 2024 up to date: –
- Lab technologist at KEMRI Kirinyaga CCDR
January 2022 to December 2023: –
- Community adult education teacher and Muringa training Centre.
March 2021 to August 2024: –
- Lab technician at Kibumbu secondary school.
January 2020 to March 2021
- Lab technician at our lady of mercy girls secondary school.
September 2015 to August 2016
- Lab technician at Kiangondu secondary school.
September 2006 to November 2006
Contribution to Science
Ms. Doreen is currently developing a research proposal examining pesticide residues and their contribution to cancer. Through this work, she aims to identify and promote a positive outcome by developing an alternative, naturally derived pesticide that farmers in the community can use to achieve high crop yields while simultaneously preventing crop diseases. It is anticipated that this initiative will address both economic challenges and public health concerns within the community.

Ms. Ruth Wambui Wachira
Senior Community Health Worker
Ms. Ruth is a senior community health worker holding an MSc in Environmental Studies and Community Development. She actively supports and assists in field projects across Kirinyaga County. She has played a key role in the JICA pilot program focused on the elimination of schistosomiasis and soil-transmitted helminths among school-going children in Kirinyaga County. Her responsibilities in this program included health education, stool sample collection and examination, and drug administration in schools.
In addition, Ms. Ruth has been involved in school-based training initiatives in Mwea, promoting proper handwashing practices and the sustainability of “leaky tin” handwashing facilities. She has supported the distribution of mosquito nets in selected villages and participated in the biological control of snails along irrigation canals through the introduction of crayfish in Mwea.
Furthermore, Ms. Ruth has served as a National Master Trainer across the Republic of Kenya. She has also contributed to the ongoing Uji-Plus program in Mwea, supporting its consumption among children, vulnerable populations, and the elderly for both nutritional and therapeutic benefits.
Education
- MSC Environmental Studies Community Development 2016-2023 Kenyatta University,
- Bachelor of Education Early Childhood Education 2013-2016 Kenyatta University,
- Proficiency Certificate in Management skills for Senior managers 2018, Kirinyaga University,
- Advanced Diploma in Community Based Development and Project Management 2009-2010 Premese Africa Development Institute,
- Diploma in Community Based Development and Project Management 2007-2008, Premise Africa Development Institute,
- Diploma in Community Based Development(Community Health Concentration) 2009-2010 Premese Africa Development Institute
- Primary Teacher certificate 2000-2002, Moi TTC Baringo,
- CITI Training Course 2025, Affiliation with KEMRI.
Positions and Scientific Appointments
- Appointed Secretary to CSC 2025
- Appointed the CCDRs team leader/Champion on Biosafety and Biosecurity
- Senior Community Health Worker 2016.
- Customer Information Desk Officer (CIDO)
Contribution to Science
- The pilot JICA program that was initiated in Mwea on elimination of schistosomiasis and soil transmitted helminthes in all the school going children in 2023, gave birth to the National deworming in all school going children as worms were declared a National disaster in the entire Republic of Kenya because it was established that worms interfere with the cognitive development of children.
- The introduction of clay fish to the water canals acted as a biological control to the Schistosomiasis snails that spread Bilhazia and this has impacted research goals at KEMRI and the communities in Mwea.
- The introduction of leaky tins for hand wash in the schools has contributed to diseases control brought about through contaminations and the soil transmitted helminthes thus bringing the worm burden down due to observing proper hygiene, sanitation and good health practices both at home and in schools environments
- The introduction of Uji- plus supplement uptake to the children and community at large has acted as a nutritional and therapeutic benefit in the control of soil transmitted helminthes rather than taking albedazole to bring worm burden down.
- The health education to the schools going children and the community stakeholders has also contributed to knowledge acquirement to basic control of many communicable diseases and proper sanitation techniques in the area.

Ms. Anjelina Lopurudoi
Field Assistant
Ms. Anjelina Lopurudoi is a Research Field Assistant with a strong professional background in Community Health and Development. She has been working with the Kenya Medical Research Institute (KEMRI), Centre for Community-Driven Research, under the Turkana Health and Genomics Project since November 2024.
In her role, Ms. Lopurudoi provides critical support to field-based research activities, including community engagement, translation of research tools and interviews, administration of structured and semi-structured interviews, and field-level data collection. She also contributes to data management processes, ensuring accuracy, completeness, and adherence to research ethics and quality standards.
Her work is instrumental in strengthening community–researcher linkages and facilitating culturally appropriate data collection, thereby enhancing the quality and impact of health and genomics research conducted for Turkana People.
Education
Kenya Institute of Management (2025 -2026)
- Training in Project Management- Certificate
Stout Vocational Rehabilitation Institute (SVRI) E- learning platform- January 2026
- One month training on an introduction to participatory approaches for childhood sexual violence research- Certificate
CITI program training under KEMRI affiliation- April 2025 [continuous program.]
- Three weeks training in Biomedical research -Basic course/refresher – certificate
CITI program training under KEMRI affiliation- May 2025
- Two weeks training in Social and behavioral responsible conduct of research- Certificate
CITI program training under KEMRI affiliation-May 2025
-
- Two weeks training in Good clinical practice course- Certificate
Positions and Scientific Appointments
KEMRI –Kirinyaga –Centre for Community Driven Research [CCDR]-From Nov 2024 to date
- Research Field assistant
Mpala Research Centre- From June 2022 to Nov 2024
-
- Research Field assistant

Mr. Fredrick Were Inzofu
Laboratory Technician
Mr. Fredrick is a registered, certified, and licensed Medical Laboratory Technologist accredited by the Kenya Medical Laboratory Technicians and Technologists Board (KMLTTB), with over ten years of professional experience in medical laboratory science, public health research, and health systems strengthening. He is currently stationed at the Kenya Medical Research Institute (KEMRI) – Centre for Community-Driven Research, where he supports the implementation of the Turkana Health and Genomics Project (THGP).
Within THGP, Mr. Fredrick contributes to multidisciplinary research evaluating cardio-metabolic health transitions associated with environmental exposures, lifestyle changes, and genetic determinants among pastoralist populations, particularly the Turkana community. He is also involved in studies exploring the hygiene hypothesis and immune modulation, with a specific focus on the interaction between soil-transmitted helminth infections and human immune responses. His work contributes to generating evidence that informs context-specific public health interventions.
Prior to joining KEMRI, he worked under a USAID-supported program as a Medical Laboratory Technologist and Sub-County HIV/TB Lead Mentor in Kakamega County. In this capacity, he provided technical leadership, mentorship, and oversight for HIV and TB diagnostic services, quality improvement initiatives, and capacity-building activities across multiple health facilities, thereby strengthening service delivery and ensuring compliance with national and international standards. He also previously served as a Field Medical Laboratory Technologist during the Kenya Population-based HIV Impact Assessment (KENPHIA 2018), where he gained extensive experience in national and international HIV surveillance research, laboratory quality assurance, specimen management, and the ethical conduct of large-scale population-based studies.
Mr. Fredrick demonstrates strong professional competencies in laboratory diagnostics, quality management systems, biosafety and biosecurity, leadership, training, mentorship, and field research coordination. He is currently pursuing a Bachelor of Science in Medical Laboratory Science at Mount Kenya University, further strengthening his academic foundation and technical expertise.
He maintains a sustained professional interest in medical microbiology and molecular biology and aspires to contribute to translational and implementation research that bridges laboratory science, public health practice, and health systems strengthening in low- and middle-income settings.
Education
| · Current | Mount Kenya University, Kenya – [Part time]
Bachelor of Science in Medical Laboratory Science (Ongoing) |
| · Dec 2015 | Kenya Medical Training College (KMTC)
Three years Training in Diploma in Medical Laboratory Sciences. |
| · Jan 2019 | Amani Counselling Centre & Training Institute
Three weeks training in comprehensive quality HIV testing and Counselling Services -Certificate |
| · 2018 & 2023 | Global Health Training Centre
Three-month training in Good Clinical Laboratory Practice and clinical research trial ethics- Certificate awarded. |
| · Dec 2025 | Global Health training Centre
Two weeks Training in ICH Good Clinical Practice (GCP) E6 (R3) – Certificate awarded. |
| · Apl 2025 | CITI Program (KEMRI Affiliation)
Three months Training in Research Trials Project: Biomedical Research, Responsible Conduct of Research, Good Clinical Practice, IRB Chair & Antibodies Production – Certificate awarded |
| · Aug 2024 | Ministry of Health (Kenya) / AMREF Health Africa
Three-month Training in Integrated Tuberculosis, Leprosy & Lung Disease Management – Certificate awarded |
| · July 2024 | Ministry of Health (Kenya) / ACQUIRE QI Leadership Program
Three weeks training in Continuous Quality Improvement (CQI) – Certificate awarded |
| · May 2024 | MOH In collaboration with Cambridge University Global Health partnership & MMUST.
One week Training in Antimicrobial Resistance (AMR) Stewardship Program-Certificate awarded. |
| · Sep 2023 | MOH – Division of Biosafety & Biosecurity, Kakamega
One week Certification Training in Laboratory Biosafety & Biosecurity in Health Systems (Level II) – Certificate awarded. |
| · July 2023 | MOH – Division of TB, Leprosy & Lung Disease Program
Three weeks training in Real-Time PCR TB Testing (Truenat Platform) & TB Microscopy-Certificate |
| · June 2023 | MOH In Collaboration with AMREF Health Africa
Three month training in quality Malaria Case management and basic laboratory malaria microscopy-Certificate awarded. |
| · June 2022 | Ministry of Health-NASCOP
Two week Certification training in Safe Phlebotomy Practice for Health Workers – Certificate awarded |
| · April 2022 | AMREF Health Africa.
Three month Training in quality Leadership Management and Governance for Health Systems Strengthening Services -Certificate awarded |
| · June 2021 | University of Nairobi In collaboration with NASCOP
Two weeks Training in Case-Based HIV Surveillance (CBS) – Certificate awarded. |
Positions and Scientific Appointments
| Duration | Institution & Position / Appointment |
| Nov 2024 – Present | Kenya Medical Research Institute (KEMRI) – Centre for Community Driven Research (CCDR)
v Medical Laboratory Technologist |
| Oct 2022 – Oct 2024 | USAID PATH – Nuru Ya Mtoto Project -Navakholo Sub-County Hospital
v Medical Laboratory Technologist & Sub-County HIV and TB Lead Mentor |
| Aug 2020 – Sept 2022 | USAID AMPATH Plus & JOOUST Boresha Jamii Project -Navakholo Sub-County Hospital
v Medical Laboratory Technologist |
| Feb 2019 – July 2020 | Africa Inuka Hospital Ltd
v Medical Laboratory Technologist & Laboratory In-Charge |
| Mar 2018 – Feb 2019 | Ministry of Health (MOH) – NASCOP, KENPHIA 2018 Survey Project
v Field Medical Laboratory Technologist |
| Feb 2016 – Feb 2018 | Bliss GVS Healthcare Ltd – Kitale Branch
v Medical Laboratory Technologist & Laboratory In-Charge |

Ms. Patriciah Kinyua Waruguru
Research Scientist
Patriciah serves as a Graduate Assistant Research Scientist at the Centre for Community-Driven Research. Her research integrates molecular, immunological, and genomic workflows to elucidate host–pathogen interactions, human evolutionary processes, and mechanisms of immune modulation. She has specialized training in bioinformatics and data analysis, which strengthens her capacity to interpret complex biological datasets and translate findings into strategies that advance public health outcomes.
Her work investigates how environmental exposures, lifestyle factors, and microbial diversity shape immune development early in life, guided by the framework of the hygiene hypothesis. She has contributed to both field sample collection and laboratory analyses, including transcriptomic and DNA methylation profiling, to identify mechanisms through which early-life exposures become biologically embedded and influence lifelong physiology. Working with the Turkana population in Kenya, her research examines how ecological exposures, phenotypic variation, and genetic adaptation influence the prevalence of allergies and asthma, thereby generating scientific evidence to inform sustainable, population-level interventions.
In addition, Patriciah’s recent research interests extend to exploring natural products as alternative therapeutic options to address the growing burden of antimicrobial resistance (AMR) and non-communicable diseases, which remain challenging to manage with existing medicines. She is particularly interested in the evolving role of ethnobotanical practices within underrepresented communities, especially in the context of climate change, which may affect the adaptability and bioactive potential of medicinal plants. She is committed to optimizing the use of medicinal herbs to enhance healthcare outcomes through evidence-based approaches.
Education
- Master of Science in Molecular Biology and Bioinformatics | Sept 2024
Jomo Kenyatta University of Agriculture and Technology, Kenya,
Department of Biochemistry,
Project in progress: Antibacterial efficacy and Bioactivity of selected plants against Klebsiella pneumoniae and Streptococcus pyogenes, and their potential mode of action.
- Bachelor of Science in Zoology and Botany with Information Technology | April 2019
Maseno University, Department of Physical Sciences,
Project: Susceptibility of Anopheles gambiae females from different ecological
sites to fungal infection.
Positions and Scientific Appointments
November 2024 – Present Graduate Student, Evolutionary and Functional Genomics
Kenya Medical Research Institute (KEMRI)
July 2021 – August 2023 Assistant Genomics Laboratory Coordinator
Mpala Research Centre
July 2019 – June 2021 Research Assistant
Institute of Primate Research, Kenya
Projects associated with member
The Turkana Health and Genomics project– Since 2018 to date
An international and collaborative project studying the role of genotype and lifestyle change on human health. Major objectives being contrasting between transcriptomic and phenotypic data to not only allow us retrace human evolutionary history but also understand how disruption of locally adapted systems may lead to disease. |NIH Funded.
Projects associated with member
2025:
- AJ Lea, IV Caldas, KM Garske, ER Gerlinger, JP Arroyo, J Echwa, M Gurven, C Handley, JC Kahumbu, J Kamau, P Kinyua, F Lotukoi, A Lopurudoi, S Lowasa, SN Njeru, R Mallarino, DJ Martins, PW Messer, C Miano, B Muhoya, J Peng, T Phung, JD Rabinowitz, A Roichman, R Siford, AC Stone, AM Taravella Oill, S Mathew, MA Wilson, JF Ayroles. (2025). Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. Science, 389(6766), 1246-1251. https://doi.org/10.1126/science.adv2467
- Marina M Watowich, Layla Brassington, Amy Longtin, Selina Wang, Ryan Rossow, Kathleen D Reinhardt, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles Miano, Benjamin Muhoya, Boniface Mukoma, Kar Lye Tam, Yvonne AL Lim, Dino Martins, Sospeter Ngoci Njeru, Kee Seong Ng, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Michael Gurven, Thomas S Kraft, Amanda J Lea. (2025). Urbanization exacerbates age-associated declines in cardiometabolic health in Turkana and Orang Asli. doi: https://doi.org/10.1101/2025.06.06.25329160
2024
- Marina M Watowich, Audrey M Arner, Selina Wang, Echwa John, John C Kahumbu, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Charles M Mwai, Benjamin Muhoya, Boniface Mukoma, Kar Lye Tam, Michael Gurven, Yvonne AL Lim, Dino Martins, Sospeter Njeru, Ng Kee Seong, Vivek V Venkataraman, Ian J Wallace, Julien F Ayroles, Thomas S Kraft, Amanda J Lea. (2024). The built environment is more predictive of cardiometabolic health than other aspects of lifestyle in two rapidly transitioning Indigenous populations. doi: https://doi.org/10.1101/2024.08.26.24312234
- Audrey M Arner, Benjamin Muhoya, Mitchell Sanchez Rozado, Michael Gurven, John Kahumbu, Joseph Kamau, Patriciah Kinyua, Francis Lotukoi, Dino J Martins, Charles Miano, Michael J Montague, Sospeter N Njeru, Julie Peng, Peter Straub, Marina M Watowich, Lea K Davis, Noah Snyder-Mackler, Julien F Ayroles, Amanda J Lea. (2024). Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch. bioRxiv,doi: https://doi.org/10.1101/2024.02.13.580011
Flash talks_ 51st Meeting Human Biology Association | 2026
- Urbanization Does Not Always Mean Loss: Microbiome Diversity Patterns in the Turkana of Kenya.
Kahumbu, John; Atkins, Thomas; Henry, Lucas; Kinyua, Patricia; Lea, Amanda; Martins, Dino; Miano, Charles; Muhoya, Benjamin; Ayroles, Julien
Biology of Genomes: Cold Spring Harbor Posters | 2025
- Dysregulation of cellular signaling networks upon rapid environmental shift. Thomas K. Atkins, Kristina M. Garske, Charles M. Mwai, Julie Peng, Matt Chao, Emma Gerlinger, John Kahumbu, Boniface Mukoma, Echwa John, Patricia Kinyua, Anjelina Lopurudoi, Nicholas Mutai, Dino Martins, Amanda Lea, Julien F. Ayroles.
Affiliation: Princeton University, Princeton, New Jersey.
https://meetings.cshl.edu/posters/genome25/genome2025_AbstractBook.pdf
- Detection of early metabolic stress mechanisms driving risk for cardiometabolic disorders in an urban- transitioning Kenyan population. Kristina M. Garske, Thomas Atkins, Emma Gerlinger, Julie Peng, Matthew Chao, John C. Kahumbu, Varada Abhyankar, Benjamin Muhoya, Charles M. Mwai, Patricia Kinyua, Anjelina Lopurudoi, Francis Lotukoi, Boniface Mukoma, Dino Martins, Sospeter Njeru, Amanda J. Lea, Julien F. Ayroles.
Affiliation: Princeton University, Princeton, New Jersey.
https://meetings.cshl.edu/posters/genome25/genome2025_AbstractBook.pdf
