Acqering samples for CD4 count using FACSCaliber


The present CRDR was built in the early seventies with its extension put up in 1980.  Throughout this period the Centre has distinguished itself in contributing a lot of information regarding diagnosis and treatment of Tuberculosis.

In the course of implementing its mandates to carry out research on Lung Health and other respiratory diseases, the Centre has also shed light on challenges such as Asthma, tobacco smoking and industrial Health.


To be a leading Centre of Excellency in respiratory diseases research nationally, towards the improvement of human health.


To conduct research on respiratory diseases of public health importance in order to improve the health of Kenyans

Mandates/ Functions

  1. TB epidemiology, case finding and holding, immunization (vaccination), pharmacotherapy of TB and pharmacoepidemiology of drug resistance TB
  2. Non-TB respiratory diseases: high priority pathologies eg. Bronchial asthma, industrial respiratory implications, Lung function (COPD)  and acute respiratory infections.
  3. Immunology of the TB and allergic conditions.
  4. Environmental and occupational health.

Ongoing Projects

  1. Vaccine trials for TB, COVID-19, Marburg Disease and yellow fever (Assessment of  efficacy, safety, and immunogenicity)
  2. Clinical trials for sickle cell disease pharmaco-products for improvement of quality of life
  3. Study to evaluate the efficacy and safety of astegolimab in patients with chronic obstructive pulmonary disease
  4. Epidemiologic, Transmission, Immunogenetic and Diagnostic Studies of Mycobacterium tuberculosis
  5. Burden of Obstructive Lung Disease in Nairobi and its environs
  6. Study on Quality of Life of Leprosy Patients
  7. Evaluation Studies to support improved community access to LPG for cooking
  8. Assessment of impact on health and environment on transition to clean energy use for cooking
  9. From Fuel To Pot: To build an interdisciplinary partnership of community members, stakeholders and researchers working on the issue of cooking using solid fuels in informal settlements (in Kenya and Malawi).
  10. Geomatic mapping of indoor fungi and their associated respiratory health effects in residential environments
  11. Health system strengthening, Assessment of diagnostic accuracy of diabetic retinopathy among frontline health care workers
  12. The burden of tobacco use among tobacco related illnesses
  13. An assessment of tuberculosis stigma index
  14. Immunology studies:
    • Role of IL-17 Cytokine Networks in TB Relapse Due to HIV
    • Paeditric TB diagnosis: Determine diagnostic performance of blood-based nPES Mtb-EV detection for pediatric TB diagnosis
    • Clinical and immunological impacts of SARS-CoV-2 infection on MTB-infected and uninfected individuals in Kenya
  15. Non-TB Chronic Respiratory Diseases research; Non-communicable lung disease in Kenya: from burden and early life determinants to participatory inter-disciplinary solutions (TUPUMUE)
  16. Centre hosts the Sub-Saharan African Centre of Excellence in air pollution monitoring, prevention and health; A Centre of Excellence in air pollution and training hub    (professional courses on household air pollution and health) and (cross-partnership PhD program in air pollution and clean energy research)

Completed Projects


Clinical Sciences Research

The division is responsible for providing a platform for undertaking phase I -IV clinical trials and patient care for respiratory diseases and related conditions.

Public Health and Operations Research

The division is responsible for undertaking public health and operational research in infectious and non-communicable respiratory diseases and their related conditions including chronic lung diseases, chronic obstructive pulmonary disease (COPD), bronchiectasis, asthma and associated risks and lung exposures such as air pollution, occupational exposure and tobacco. Including cancer diagnostic/treatment studies including looking at survival

Epidemiology and Surveillance

The division is responsible for undertaking epidemiological studies in adults, adolescents and infants for tuberculosis, pneumonia and other lung diseases and monitor lung disease trends through surveillance.


The division is responsible for undertaking research in biomedical sciences and provide diagnostic services for study participants and the public.

Non-communicable Disease (NCDs)

Research in NCDs that are related to lung disease eg. Diabetes, Lung cancer


  1. Ministry of Health, Kenya
  2. Global Blood Therapeutics, Inc.
  3. Sanofi Pasteur Inc.
  4. Serum Institute of India Private Limited (SIIPL)
  5. National Institute of Health (NIH)
  6. Bill & Melinda Gates Medical Research Institute (Gates MRI)
  7. Hoffmann-La Roche Ltd
  8. University of Stirling,UK
  9. National Research Fund-Kenya,
  10. Liverpool School of Tropical Medicine
  11. Equity Bank Foundation
  12. Berkeley Air Monitoring Group (BAM)
  13. University of Liverpool
  14. Measurement Technology Laboratories (MTL)
  15. Columbia University
  16. World Health Organization.
  17. AMREF Health Africa

Dr Jane Rahedi Ong’ang’o

Deputy Director Centre for Respiratory Disease Research

Dr Jane Rahedi Ong’ang’o is a medical doctor and Principal Research Scientist working at the Centre for Respiratory Diseases Research, Kenya Medical Research Institute (KEMRI). Currently she heads this Centre as the Deputy Director. She is a Public Health Specialist with an interest in health programme implementation and operational research of interventions geared towards control of both communicable and non-communicable conditions. She has played the role of principal investigator for various population based surveys and also served as a research team coordinator.


We offer services in:

  • HIV comprehensive care clinic



  1. Pan African Mycology working group Meeting in (May 30-31, 2023)
  2. Pan African Thoracic Society Congress (June 7 -10, 2023)
  3. Kenya International Lung Health Conference

Contact Info

P.O.Box 47855-0100.
Nairobi, Kenya

TEL       +254-020-2719601 / +254-020-2724264/5

E-mail: moc.liamgobfsctd@irmekrdrc.