CENTER CLINICAL RESEARCH (CCR)-NAIROBI
Overview
The Centre for clinical research (CCR) was established in 1985 as a clinical trials unit to support development of drugs and vaccines aimed at tackling priority disease conditions in the country. It has grown over time and established linkages with key institutions and partners notably the United States Medical Research Unit (USAMRU) , Drugs for Neglected Diseases Initiative (DNDi), where KEMRI is a founding member, the University of Washington, Foundation for Innovative New Diagnostics (FIND) , University of Texas Medical Branch (UTMB).The centre scientists have undertaken numerous clinical trials initially these were for the treatment of leishmaniasis (kala azar) in children. During this inception years, CCR was a must visit site for the university of Nairobi Medical students to understand the value of research in drug development and the appropriate treatment of patients.
Mission
To improve human health and quality of life through research, capacity building and service delivery
Vision
To be a globally recognized Centre of excellence in human health research.
Mandates
- Undertake research in communicable and Non communicable diseases.
- Provide a platform for clinical trials (drug safety and efficacy) in neglected, communicable and non-communicable diseases.
- Provide a conducive environment for patient/ participant monitoring, support and safety.
Products and services offered
- Laboratory diagnostics
- Diagnostic imaging services. General X-Ray and Ultrasonography
- Endoscopy services
- General outpatient services
- Pharmacy dispensing services
- Catering services
- Laundry services
Functions
- Undertake research in Communicable and Non-Communicable Diseases
- Provide a platform for clinical trials (drug safety and efficacy) in Neglected, Communicable and Non-Communicable Diseases
- Provide a conducive environment for patient/participant monitoring, support and safety
- Test new therapies, tools and vaccines for new therapies
Ongoing Projects
- A demographic surveillance system (DSS) in the previous bed net study area aimed at establishing a high quality surveillance system in a population of 135,000 and provide an infrastructure that will yield reliable demographic
data and serve as a platform to evaluate the impact of public health interventions on morbidity and mortality. - Population genetics of malaria vectors.
- The effects of climate change on human health.
- The epidemiology and immunology of malaria epidemics in the highlands.
Completed Projects
- A community-based trial on the impact of insecticide-treated bed nets on childhood morbidity and mortality in an area of intense and perennial malaria transmission in western Kenya,
- The interaction of malaria and HIV in pregnant women and the immuno-epidemiology of malaria in western Kenya,
- The Asembo Bay Cohort Project.
undertake research in digestive and liver diseases and provide solutions for digestive conditions and also provide therapeutic services to study participants.
GASTROINTESTINAL DISEASES RESEARCH DIVISION
the unit spearheads mental health research including drug and substance use
MENTAL HEALTH RESEARCH
ENT/ Head and Neck Research
Conduct studies on epidemiology, diagnosis , treatment, prevention and control in:
Communicable diseases (such as; malaria, HIV, STI,TB, hepatitis, diarrheal diseases)
LABORATORY DIVISION
Provide safe and accurate medical Diagnostic Radiological images that improves upon the institute’s quality research and service
RADIOLOGY DIVISION
Clinical trials are undertaken at the Nairobi Station and the county stations of Thika, Kisumu, Kericho.
CLINICAL TRIALS DIVISION
Division addresses infectious diseases and the neglected diseases particularly diarrheal diseases, Leishmaniasis and other emerging diseases
INFECTIOUS AND PARASITIC<br /> DISEASES RESEARCH
Division addresses infectious diseases and the neglected diseases particularly diarrheal diseases, Leishmaniasis and other emerging diseases
BASIC SCIENCE RESEARCH PROGRAM
In the division the mandate is to undertake research in Neglected Tropical Diseases (NTD’s) with special emphasis of Visceral Leishmaniasis (VL) which is the most serious form of the disease.
NEGLECTED DISEASES RESEARCH
Overview
The Cancer Registry at KEMRI began in 2001 as a project funded by the US National Cancer Institute, focusing on the population of Nairobi province (now Nairobi County). This was after consultations with key stakeholders including Ministry of Health, World Health Organisation (WHO) and key treatment facilities. In 2012 it was established as a unit within the Centre for Clinical Research (CCR) and more staffing were hired and deployed to the unit. In 2016 through a grant from the Kenya Government (National Treasury) and the US National Cancer Institute (https://www.cancer.gov/) the registry was expanded to cover more counties and a central repository, the Kenya Cancer Registry, was established to pool the population-based data. The KEMRI Cancer Registry is thus an integrated national Population-Based Cancer Registry (PBCR) that aims to provide high quality cancer surveillance data including incidence, mortality, survival, to support scientific research and inform cancer control initiatives in the country. The following counties signed MoU’s with KEMRI to develop population-based registries and be part of the KEMRI program: Nairobi, Uasin Gishu (Eldoret), Kisumu, Meru, Embu, Mombasa, Garissa, Nakuru, Kitui, Kakamega, Machakos and Kiambu (see map). The Nairobi and Eldoret registries are founding members of the East Africa Cancer Registry Network that was expanded to be the Africa Cancer Registry Network (AFCRN) (http://afcrn.org/) in 2012. The two registries have continuously participated in AFCRN activities including joint research with other sub-Saharan African countries, trainings, technical support among others. The two registries are also members of the International Association of Cancer Registries (IACR) (http://www.iacr.com.fr/) and have met the quality standards for PBCRs as per the International Agency for Research on Cancer (IARC) (https://www.iarc.fr/) and IACR’s guidelines. The data is thus utilized to generate estimates for Kenya published in IARC’s GlOBOCAN (http://gco.iarc.fr/) series. Data from Nairobi registry was included in volume XI of the prestigious. READ MORE
Contact Info
Kenya Medical Research Institute Headquarters,
Nairobi. off Mbagathi way,
P.O BOX 20778 – 00200 Nairobi
Tel: 2720781
E-mail: gro.irmek@rcc